Simultaneous Dual-Color Fluorescence Microscope: A Characterization Study
نویسندگان
چکیده
منابع مشابه
Simultaneous Dual-Color Fluorescence Microscope: A Characterization Study
BACKGROUND High spatial resolution and geometric accuracy is crucial for chromosomal analysis of clinical cytogenetic applications. High resolution and rapid simultaneous acquisition of multiple fluorescent wavelengths can be achieved by utilizing concurrent imaging with multiple detectors. However, such class of microscopic systems functions differently from traditional fluorescence microscope...
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Jan Wolfgang Krieger,1,† Anand Pratap Singh,2,†, Christoph S. Garbe,3 Thorsten Wohland,2 and Jörg Langowski,1,∗ 1German Cancer Research Center (DKFZ), Biophysics of Macromolecules (B040), Im Neuenheimer Feld 580, D-69120 Heidelberg, Germany, 2Departments of Biological Sciences and Chemistry and NUS Centre for Bio-Imaging Sciences, National University of Singapore, 14 science Drive 4, Singapore ...
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Confocal fluorescence correlation spectroscopy as a time-averaging fluctuation analysis combining maximum sensitivity with high statistical confidence has proved to be a very versatile and powerful tool for detection and temporal investigation of biomolecules at ultralow concentrations on surfaces, in solutions, and in living cells. To probe the interaction of different molecular species for a ...
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Quantitative determination of the density and conformation of DNA molecules tethered to the surface can help optimize and understand DNA nanosensors and nanodevices, which use conformational or motional changes of surface-immobilized DNA for detection or actuation. We present an interferometric sensing platform that combines (i) dual-color fluorescence spectroscopy for precise axial co-localiza...
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ژورنال
عنوان ژورنال: Analytical Cellular Pathology
سال: 2013
ISSN: 2210-7177,2210-7185
DOI: 10.1155/2013/143785